Contrast agents possessing high temperature sensitivity.

نویسندگان

Mark Milne

Robert H E Hudson

چکیده

Contrast agents based on lanthanide tetra-propargyl DOTAM complexes suitable for temperature mapping by magnetic resonance spectroscopy (MRS) are reported. Sensitivity values from 1.05 ppm/°C to 1.76 ppm/°C were determined which represents an improvement of 2-3 times over currently available lanthanide temperature-responsive contrast agents.

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